SPARQL Query Recommendations by Example

In this demo paper, a SPARQL Query Recommendation Tool (called SQUIRE) based on query reformulation is presented. Based on three steps, Generalization, Specialization and Evaluation, SQUIRE implements the logic of reformulating a SPARQL query that is satisfiable w.r.t a source RDF dataset, into others that are satisfiable w.r.t a target RDF dataset. In contrast with existing approaches, SQUIRE aims at rec- ommending queries whose reformulations: i) reflect as much as possible the same intended meaning, structure, type of results and result size as the original query and ii) do not require to have a mapping between the two datasets. Based on a set of criteria to measure the similarity between the initial query and the recommended ones, SQUIRE demonstrates the feasibility of the underlying query reformulation process, ranks appropriately the recommended queries, and offers a valuable support for query recommendations over an unknown and unmapped target RDF dataset, not only assisting the user in learning the data model and content of an RDF dataset, but also supporting its use without requiring the user to have intrinsic knowledge of the data

Addressing exploitability of Smart City data

Central to a number of emerging Smart Cities are online platforms for data sharing and reuse: Data Hubs and Data Catalogues. These systems support the use of data by developers through enabling data discoverability and access. As such, the effectiveness of a Data Catalogue can be seen as the way in which it supports `data exploitability': the ability to assess whether the provided data is appropriate to the given task. Beyond technical compatibility, this also regards validating the policies attached to data. Here, we present a methodology to enable Smart City Data Hubs to better address exploitability by considering the way policies propagate across the data flows applied in the system

SPARQL Query Recommendation by Example: Assessing the Impact of Structural Analysis on Star-Shaped Queries

One of the existing query recommendation strategies for unknown datasets is "by example", i.e. based on a query that the user already knows how to formulate on another dataset within a similar domain. In this paper we measure what contribution a structural analysis of the query and the datasets can bring to a recommendation strategy, to go alongside approaches that provide a semantic analysis. Here we concentrate on the case of star-shaped SPARQL queries over RDF datasets. The illustrated strategy performs a least general generalization on the given query, computes the specializations of it that are satisfiable by the target dataset, and organizes them into a graph. It then visits the graph to recommend first the reformulated queries that reflect the original query as closely as possible. This approach does not rely upon a semantic mapping between the two datasets. An implementation as part of the SQUIRE query recommendation library is discussed

Prognostic relevance of ALT-associated markers in liposarcoma: a comparative analysis

<p>Abstract</p> <p>Background</p> <p>Most cancers maintain telomeres by activating telomerase but a significant minority, mainly of mesenchymal origin, utilize an alternative lengthening of telomeres (ALT) mechanism.</p> <p>Methods</p> <p>In this study we comparatively analyzed the prognostic relevance of ALT in a monoinstitutional series of 85 liposarcoma patients as a function of the marker (ALT-associated promyelocytic leukemia bodies (APB) versus heterogeneous telomeres) used to classify the tumor.</p> <p>Results</p> <p>Independently of the detection approach, ALT proved to be a prognostic discriminant of increased mortality, although the prognostic relevance of the two markers appeared at different follow-up intervals (at 10 years for APB and 15 years for telomeres).</p> <p>Conclusions</p> <p>Overall, we confirmed ALT as an indicator of poor clinical outcome in this disease and provide the first evidence that the sensitivity of the ALT predictive power depends, at least in part, on the method used.</p

Traditional vs. novel approaches to coastal risk management: A review and insights from Italy

Coastal areas frequently face critical conditions due to the lack of adequate forms of land use planning, environmental management and inappropriate coastal risk management, sometimes leading to unexpected and undesired environmental effects. Risk management also involves cultural aspects, including perception. However, the acknowledgement of risk perception by stakeholders and local communities, as one of the social pillars of risk analysis, is often lacking.. Starting from an overview of the risk concept and the related approaches to be addressed, the paper investigates the evolution of coastal risk management with a focus on the Italian case study. Despite the design and adoption of national policies to deal with coastal risks, coastal management still shows in Italy a fragmented and poorly coordinated approach, together with a general lack of attention to stakeholder involvement. Recent efforts in the design of plans aiming at reducing risks derived from climate change and mitigating their impacts (National Strategy on Climate Change Adaptation; National Climate Change Adaptation Plan; National Recovery and Resilience Plan activities) should be effective in updating knowledge about climate change risks and in supporting national adaptation policies

Dealing with diversity in a smart-city datahub

In this paper, we present the data curation approach taken by the MK:Smart project, creating a large data repository of datasets about all aspects of the city of Milton Keynes in the UK and its citizens. The issues faced here, which we believe will become more and more common to large, data-centric smart-cities initiatives, is the one associated with the diversity of these thousands of datasets in terms of the licenses, policies and terms they are associated with them. We describe this repository of datasets, the MK Datahub, and its architecture to create data workflows from original sources to applications. We focus on the approach taken to record, in a structured, ontology-based way the components of the licenses and policies of each dataset, as well as the tools we are developing to manage such representations and to reason with them

Analysis of the human Y-chromosome haplogroup Q characterizes ancient population movements in Eurasia and the Americas

Background: Recent genome studies of modern and ancient samples have proposed that Native Americans derive from a subset of the Eurasian gene pool carried to America by an ancestral Beringian population, from which two well-differentiated components originated and subsequently mixed in different proportion during their spread in the Americas. To assess the timing, places of origin and extent of admixture between these components, we performed an analysis of the Y-chromosome haplogroup Q, which is the only Pan-American haplogroup and accounts for virtually all Native American Y chromosomes in Mesoamerica and South America. Results: Our analyses of 1.5 Mb of 152 Y chromosomes, 34 re-sequenced in this work, support a "coastal and inland routes scenario" for the first entrance of modern humans in North America. We show a major phase of male population growth in the Americas after 15 thousand years ago (kya), followed by a period of constant population size from 8 to 3 kya, after which a secondary sign of growth was registered. The estimated dates of the first expansion in Mesoamerica and the Isthmo-Colombian Area, mainly revealed by haplogroup Q-Z780, suggest an entrance in South America prior to 15 kya. During the global constant population size phase, local South American hints of growth were registered by different Q-M848 sub-clades. These expansion events, which started during the Holocene with the improvement of climatic conditions, can be ascribed to multiple cultural changes rather than a steady population growth and a single cohesive culture diffusion as it occurred in Europe. Conclusions: We established and dated a detailed haplogroup Q phylogeny that provides new insights into the geographic distribution of its Eurasian and American branches in modern and ancient samples

Combined Arthroscopic-Assisted Lower Trapezius Tendon Transfer and Superior Capsule Reconstruction for Massive Irreparable Posterior-Superior Rotator Cuff Tears: Surgical Technique

Primary or revision irreparable rotator cuff tears remain a challenge. Clear algorithms do not exist. Several joint-preserving options are available, but no technique has been definitely proven to be better than another. Although superior capsule reconstruction has been shown to be effective in restoring motion, lower trapezius transfer can provide strong external rotation and abduction moment. The aim of the present article was to describe an easy and reliable technique to combine both options in 1 surgery, aiming to maximize the functional outcome by getting motion and strength back

Two new species of terrestrial-breeding frogs (Anura: Brachycephaloidea) from Cordillera de Colán, Peru

We describe two new species of terrestrial-breeding frogs from the Cordillera de Colán, in northeastern Peru. We used Parsimony and Maximum Likelihood approaches to infer a molecular phylogeny on a dataset composed of 75 terminals, including three terminals representing the new species, and 4202 bp of concatenated mtDNA and nuDNA fragments. Our phylogenetic analyses support the placement of the two new species in Lynchius and Oreobates, respectively. The new species of Lynchius occurs in two localities from 1,977 to 2,006 m a.s.l., and is characterized by having a dorsum covered by conical tubercles and a brown dorsal coloration lacking a pattern of blotches on the hidden surfaces of flanks and hindlimbs. The new species of Oreobates is only known from one location at 2608 m a.s.l. and is characterized by the absence of axillary and inguinal glands, and the presence of white or cream blotches on the dark brown hidden surfaces of the body